Background: Cushing syndrome (CS) is a multisystem disease caused by long-term exposure to
high levels of glucocorticoids. Slow development, weight gain, truncal obesity, facial plethora, and
hypertension are all characteristics. Aim: This research aimed to see how a self-learning program
affected nurses' productivity when caring for children with Cushing syndrome. A quasi
experimental approach has been utilized to assess the influence of a self-learning course on nurses'
effectiveness in caring for children with Cushing syndrome. Settings: This study was conducted in
the pediatric and hereditary units of a pediatric hospital associated with Ain Shams University.
Sample: A practical selection of all nurses working in pediatric and hereditary units (80 bedside
male and female nurses) from the starting of January 2021 to the end of June 2021. Tools of data
collection: To obtain findings for this research, two techniques were used: a standardized
interviewing survey form, as well as observational evaluations of nursing care provided to children
with CS. Results: Nurses' understanding of CS was insufficient during the pre-module phase,
although there is a statistically considerable variation between pre and post learning module
deployment. Nurses' awareness, practice, and before and post module implementation all have a
beneficial relationship. Conclusion The nurses evaluated who care for children suffering Cushing
syndrome had an inadequate level of knowledge regarding Cushing syndrome, its long-term
implications, and long-term continuous therapy. Also, after implementing the module, the studied
nurses had a competence practice level in caring for children with Cushing syndrome.
Recommendation: Enhancing nurses' understanding for value of self-learning modules on the
growth of their technical skills as well as the quality of care delivered to children with CS through
in-service training activities in various health care institutions