Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common female endocrine disorders, which affect about 5%-10% of women worldwide during their reproductive age. Aim: To evaluate the effect of educational program on lifestyle for paramedical students with polycystic ovarian syndrome. Setting: The study conducted at two government colleges in Jordan. Study Design: A Quasi- experimental (pre-test & post-test) design was utilized in this study. Sample type: A purposive sample. Sample size: 68 students. Tools of Data Collection: Identification of students with PCOS tool, Assessment of lifestyle habits tool, POCS structured interviewing questionnaire tool, Follow up sheet, and Psychological assessment tool. Results: The present study findings revealed that a highly significant difference regarding the student's knowledge about the PCOS as compared pre, post, and follow-up program results. Also, there was a significant improvement in the student's lifestyle habits after applying to the educational program compared to before applying them. Conclusion: The results of the study supported the study hypothesis that students who attend the educational program regarding polycystic ovarian syndrome, will improve their knowledge scores and their lifestyles. Recommendations: Applying a screening program for PCOS in young students is a very important to reduce the long-term health complications associated with PCOS.