Background: coronary artery bypass graft (CABG) is considered alone of the most critical surgeries in Egypt nowadays. Assessing bio psychosocial needs for patients post (CABG) is very important for facilitating their recovery and helping them cope with any health problems. Aim: This study aimed to assess bio psychosocial needs of patient post coronary artery bypass graft (CABG). Research design: Descriptive exploratory design was used to achieve the aim of this study. Setting: This study was conducted in the Cardio Thoracic Outpatient clinics at Cardio Thoracic Academy affiliated to Ain Shams University Hospital. Subject: A purposive sample of 60 adult patients' post CABG were taken to conduct this study randomly selected. Tools:1). Patient′ interviewing questionnaire, 2: Bio psychosocial needs of patients post Coronary Artery Bypass Graft assessment tool. Results:70%of patients under study had satisfactory level of knowledge regarding coronary artery bypass graft. As well as, there was higher mean score of the studied patients regarding their social needs 53.06± 13.63 rather than psychological needed 44.64±7.37 and physical need 40.74±12.53. Conclusion: The studied patients reported the social needs very much need more than the other needs, more than half of the studied patients reported psychological needs.regarding depression. Recommendations: further studies should be designed to encouraged Patients to participate in rehabilitation programs post coronary artery bypass graft surgeries to satisfy their physical, psychological and social needs.