Background: Breast Self-Examination has a role in early diagnosis and prevention of morbidity
and mortality rate of breast cancer. Promoting women knowledge, capabilities and practice are
required in this regard. Aim: Assess the effect of breast self-examination training program on
knowledge and practice of the working women in selected primary health centers. Methods: Quasi -
experimental study pre/post and follow-up after one month was conducted involving 80 women
using a purposive sample. Self -administered questionnaire to assess women demographic data,
knowledge about breast cancer, breast self-examination and also practice related to the same.
Results: Pre-program most of women had poor level of knowledge as compared to all and vast of
them had high level of knowledge post program and one month follow up, respectively. Vast of
women showed unsatisfactory level of practice pre-program compared to all of them have
satisfactory level of practice on post program and follow up. Both the knowledge and practical
competency scores showed highly significant increment after the intervention. Conclusion and
recommendation: knowledge and practice of women were improved after receiving the training
program. Women health education should occur at an earlier stage in lives with emphasis on the
healthy behaviors and practices to prevent cancer.