Background: Pediatric nursing staff have an important role in administrating of penicillin and
understanding the effect of penicillin allergy for pediatric patients. Aim of the study: This study
aimed to assess the nurses' performance regarding penicillin administration for pediatric patients.
Research Design: A descriptive design was used to this study. Setting: the study was conducted at
General Outpatient clinics of Children's Hospital Affiliated to Ain Shams University Hospitals and
Caridac Clinic. Subjects: A convenience sample was composed of 50 nurses working at the
previously mentioned settings regardless their experience, age, gender, and qualification. Tools of
data collection: (1) An interview questionnaire sheet to assess nurse knowledge about penicillin
administration (2) Observational checklist to assess nurses practice toward penicillin administration.
Results: The result found that half of the studied nurses their age were ranging between 20 years to
less than 30 years old, with mean age 22.6±1.3, and more than half of studied nurses were females,
while the minority of them had unsatisfactory level of knowledge regarding penicillin
administration and most of them were incompetent for practices regarding penicillin administration.
Conclusion: The study concluded that two thirds of the studied nurses had unsatisfactory total level
of knowledge regarding penicillin administration, while more than half of them had incompetent
total score of practices regarding penicillin administration, and there were a positive relation
between nurses' knowledge and their practices toward penicillin administration with statistical
significant difference. Recommendation: The study recommended that, periodic assessment for
nurses performance regarding penicillin administration. Developing educational and orientation
program for nurses about penicillin administration to improve their performance regarding penicillin
administration. Further studies should be conducted in large sample size in different pediatric places
to generalize information and improve nurses' knowledge and practice regarding penicillin
administration.