Background: Nursing shortage is a global concern that requires urgent strategies to retain staff nurses. Workplace violence and work engagement are critical determinants of staff nurses' intention to leave their profession. Aim: the current study aimed to investigate the relationship < strong> between workplace violence, work engagement, and staff nurses' intention to leave the nursing profession. Research Design A descriptive correlational design was used. Setting: the current study was conducted in different departments at Beni-Suef University Hospital. Subjects and Methods: A purposive sample of 135 staff nurses from the study setting. Tools: three tools were used;1- types of workplace violence questionnaire, 2-Utrecht Work Engagement Scale (UWES), and 3- staff nurses' intention to leave nursing profession questionnaire. Results: More than half of staff nurses were exposed to a high level of violence and had a lower level of work engagement (51.1% and 56%) respectively. About two third of staff nurses (64.4%) had a high level of intention to leave their profession. There was a statistically significant negative correlation between workplace violence and work engagement (P=0.001), while there was a statistically significant positive correlation between workplace violence and intention to leave (P=0.003). Also, there was statistically significant negative correlation between work engagement and intention to leave (P=0.004). Conclusion: Workplace violence and work engagement could affect staff nurses' intention to leave both the hospital and the profession. Recommendations: Nurse Managers should pay great attention to influence the work place violence, work engagement on staff nurses' intention to leave. Prevention of violence must be an inseparable part of the organization culture and organization climate. Involvement of staff nurses in organizational affaires to enhance their engagement.