The COVID-19 pandemic is considered a major challenge and source for stress among health team members specially the nurses as well as nursing students. The entire health care system is fighting for survival from the pandemic. Nurses are the front line fighters in the healthcare system. Nursing students are the future nurses and they may become the baton holders of healthcare in the near future. This study aimed to evaluate effect of adopting one of coping strategies on overcoming stress associated with nursing students' clinical training during COVID-19. Method: A quasi-experimental research design was utilized by the investigators to conduct this study. A convenient sampling technique was used to carry out this study. The number of participants was 90. Data collection tools: Three tools were used in this study: First Tool; Students' Demographic Data Assessment Tool; this tool was used to assess students' demographic characteristics as gender, age, residency, student's financial independent status, and their interest to study nursing. Second Tool; Perceived Stress Scale (PSS) was used for measuring the perception of stress during clinical training. Third Tool; Coping Behaviour Inventory Tool; this tool was used to identify coping strategies utilized by the nursing students. Results: Stated that, there was highly statistically significant difference in perceived stress level among the studied nursing students before and after adopting one coping strategy at P < 0.001. Conclusion: This study concluded that, adopting one coping strategy had statistically significant effect on reducing perceived stress level of nursing students during clinical training. Recommendation: This study recommended the importance of adopting one coping strategy to be utilized by the nursing students to reduce their stress during clinical training.