Telehealth refers to the usage of any electronic materials in the form of voice, images, documents,
etc. The aim: to examine the effect of asynchronous mobile health nursing intervention on
medications adherence and quality of life among patients with psoriasis. Design: A quasi
experimental research design. Subjects: A purposive sample including 60 patients who were
admitted to the dermatology outpatient clinics, were divided randomly into the study and control
group of 30 patients in each. Setting: This research was conducted at a university hospital
dermatology clinic. Instruments of the study: (I): Structured interview questionnaire. (II):
Modified 12-Item Medication Adherence Scale. (III): Dermatology Life Quality Index. Results:
The mean of knowledge score, adherence level was increased, and improve quality of life index
increased significantly throughout the phases of the intervention among study group subjects with
statistically significant differences existed between them. Conclusion: Using (mobile health) in
education about psoriasis and its management significantly improving total knowledge score,
medications adherence improved the quality of life. Recommendations: designing different mobile
patient engagement applications to provide a simple way for follow-up, and education. Replication
of the study using a large number of subjects, and longer follow-up time to permit a chance for
results generalization.