COVID-19 was and still one of the most serious global health care burden on patients, families, communities
as well as health care workers (HCWs). All HCWs including nurses' interns has more vital role in prevention
and caring of this infection. Thus, ongoing training for nurses' interns under the scope of mentoring is a corner
stone in continuing effective and efficient nursing care with high quality. Aim of the Study: to evaluate the
effect of mentoring program on nurse interns' knowledge, attitudes, safety practices, and psychological
readiness toward COVID-19 pandemic. Research Design: Quasi experimental one group pre/post test research
design was adopted. Setting: The present study was conducted at different training governmental and private
hospitals for nurses' interns. Subjects: A convenient sample of 179 out of 335 nurses interns were enrolled in
the study. Tools: Online web-based electronic self- administrated questionnaires were used for data collection;
I) Nurses interns' knowledge regarding COVID-19 structured questionnaire, II) Nurses interns' attitudes
regarding COVID-19 structured questionnaire, III) Nurses interns' safety practices towards COVID-19
observational checklist, and IV) Depression Anxiety Stress Scale (DASS-21)". Results: statistically significant
improvement in nurses' interns' knowledge, attitudes, safety practices levels and psychological readiness
toward COVID-19 after conducting mentorship program. Conclusion: Mentorship program positively affects
nurses' interns' levels of knowledge, attitudes, and safety practices as well as psychological readiness
Recommendation: Incorporates the mentoring program within nurses' internship training program as a basic
tool of training, to provide continuous support and ongoing evaluation of nurses' interns' knowledge, attitudes,
safety practices and psychological readiness.