Background: the level of burden is associated with severity of Alzheimer disease, frequency, and
intensity of care, and absence of help. In many cases, mostly all members of the family become a
stigma victim and could have feelings of shame about the disease. Aim: the aim of the study was to
assess relationship between caregiving burden, knowledge and stigma of caregivers caring for older
adults with Alzheimer disease. Design: the researchers used a descriptive-correlational cross
sectional design to complete the study. Subjects: A convenience sample of 108 family caregivers of
the older adults diagnosed with Alzheimer's disease covered a period of one year (from 1st of May
2019 till 1st of June Settings: This study was carried out in the general hospital at patient clinic and
Association of Alzheimer Patients at Mansoura city, Dekahlia governorate. Tools: Four tools were
used to collect the data namely; Demographic and clinical data structure interview schedule sheet,
The Zarit Burden Interview (ZBI), Alzheimer's Disease Knowledge Scale (ADKS) and The Stigma
Impact Scale (SIS): Results: The mean age of caregivers was 44.93 ± 9.135. And more than two-
thirds of the study sample were females, while the mean age of elderly was (75.32 ± 5.901). And
above half of the study subject were male (69.4%). A strong positive correlation was found between
caregiver's burden and stigma. Conclusion: A statistical significance relation was found between
all sociodemographic characteristics of family caregivers and each of caregiving burden, stigma,
and knowledge. A strong positive correlation was found between caregiver's burden and stigma.
Recommendations: Educational program for family caregivers not only about the disease processes,
but also the way to manage symptoms, experiences, detect resources that could lower the level of
caregiving burden, improve their knowledge and reduce sense of stigmatization.