Background: Schizophrenia is a chronic, persistent, frequently recurrent psychiatric
condition that affects early brain development with a heterogeneous genetic and
neurobiological history and is expressed as a mixture of psychotic symptoms such as
hallucination, delusion, disorganization, and motivational and cognitive dysfunctions . The
aim of this study Having a sense of coherence (SOC) and good social support is important
for psychological well-being. This study aimed to investigate the nature of SOC and social
support and their relationship with psychological well-being among patients with
schizophrenia. Methodology: A descriptive cross-sectional research design was used to
assess a convenience sample of 148 schizophrenia patients from Zagazig University Hospital.
Data were collected using a questionnaire consisting of a sociodemographic datasheet,
medical datasheet, SOC scale, multidimensional social support scale, and general health
questionnaire (GHQ-12). Results: Significant relationships were found between some
medical data and SOC and between social support and psychological well-being. The mean
scores for SOC and social support were significantly correlated positively with the GHQ
result. Conclusion: The highest percentage of SOC was reported on the comprehensibility
subscale, social support was mainly received from others, and low psychological well-being
was found to exist particularly for the positive statements. SOC and social support were
significant positive predictors of GHQ results. Recommendation: endorsing the application
of intervention programs for patients with schizophrenia that enhance SOC to improve their
psychological well-being and recovery from disease