Ketogenic diets (KDs) have increased popularity among patients and researchers comparable due to
their putative anti-tumor mechanisms plus its effect in reducing body weight in obese patients, and
improving glycemic& lipid metabolism of diabetic patients. Aim: The study aimed to evaluate the
effect of ketogenic diet on blood glucose level, body mass index and quality of life among breast
cancer patients with type 2 diabetes mellitus. Design: A quasi-experimental research design was
utilized. Setting: The study was conducted at inpatient department at oncology center Mansoura
University, and follows those patients at outpatient clinics. Subjects: A purposive sample of 26 type
2 diabetes mellitus breast cancer obese patients was enrolled in this study. Tools: Two tools were
used. Tool I: Structured interview questionnaire. Tool II: SF-8 Questionnaire. Results: The mean
and SD of body mass index, hemoglobin A1C and fasting blood sugar of females' patients were
34.78±7.176, 8.94±1.156 and 223.50±41.84 respectively, before starting Ketogenic diet, which
changed with significant difference to become 32.76±6.841, 7.33±0.686 and 135.00±29.28
respectively, after applying Ketogenic diet. Conclusion: The data presented in the present study
showed that a ketogenic diet can help as a natural therapy for significant weight reduction in obese
patients, glycemic control and improving quality of life for type 2 diabetic breast cancer patients.
Recommendation: This study recommended that Ketogenic diet should be incorporated in the
dietary regimen for patients suffering from obesity, breast cancer and type 2 diabetes.