Back ground Psychiatric nursing isregarded as one of the moststressful occupationsin the world. It considered as a challenging task for psychiatric nurses physically and psychologically especially nurses who are faced with specialized work demands. Design This study was descriptive study. Aim the study aimed at determine relationship between self esteem and coping patterns toward work stressors among psychiatric mental health nurses. This study conducted on 210 psychiatric mental health nurses setting Elkhanka psychiatric mental health hospital at El-khanka City Qalubia, Governorate. Type of sample was Convenience sample. Tools consisted of, four tools as the following; Tool I Interview questionnaire sheet used to assess psychiatric mental health nurses socio-demographic characteristics, Tool II Rosenberg self- esteem scale to assessself-esteem level for psychiatric mental health nurses, ToolIII Work stressorsscale to measure work stressors for psychiatric mental health nurses and Tool IV Jalowiec coping scale to measure coping patternstoward work stressorsfor psychiatric mental health nurses. Results: The study revealed that, nearly three quarter of psychiatric mental health nurses have High level of self esteem, more than two third of them have moderate work stressors level and higher percentage of them have effective coping pattern. Conclusion the study revealed that there was positive correlation and significant relation between self esteem and coping pattern toward work stressors among psychiatric mental health nurses. Recommendation, The study recommended that Reconsider instructional program for psychiatric nurses on how to reduce the job stressors. The future research should be done with a larger sample size in several psychiatric hospitals and in a broader geographical area