Background: Human Immunodeficiency Virus (HIV) has become one of the most serious
challenges to public health due to its high morbidity, mortality and economic impacts. Knowledge
and positive attitudes are important aspects of providing nursing care for people living with
HIV/AIDS. Aim: This study aimed to assess knowledge, attitudes and practices of nurses
working with HIV/AIDS patients. Methods: this study was exploratory descriptive, performed on
65 nurses working with HIV/AIDS patients at El-Homiaat Hospital. Data were collected using A)
Interviewing Questionnaire1- Socio demographic questionnaire, 2- HIV Knowledge
Questionnaire (HIV-KQ-18)3-AIDS Attitude Scale (AAS) and B) Nurses' Practice Checklist
(NPC). Results: The result of this study showed that nurses working with HIV/AIDS patients
possesssatisfying level of knowledge about transmission and non-transmission routes (78.5%)
andunsatisfying knowledge about preventive methods especially safe sexual practice (44.6%).
However, nurses under study showed high level of empathic attitude toward people living with
HIV/AIDS (78.5%), high level of avoidance were observed (72.3%). Regarding practice, nurses
under study showed lack of proper use of communication skills (80%) with adherence to safety
measures (89.2%) with HIV/AIDS patients. Nurses with bachelor degree showed satisfying
practice of both communication skills and safety measures. Conclusions:There were satisfying
knowledge, negative attitudes and unsatisfying practice level among nurses under
study.Recommendations:Training should focus on Preventive methods and modes of HIV
transmission, care and support of all patients no matter what the disease, emphasizing
confidentiality as patient right that should not be ignored and monitor nurses' communication
skills