Ureteral stents represent effective drainage method to preserve renal function, treat pain caused by ureteral obstruction. Aim: this study aimed to determine the effect of educational interventions for nurses about pre and post-operative care on clinical outcomes of patients undergoing ureteral stent surgery: Subject and Method, Design & Setting: quasi- experimental was conducted in this study in the Urology Department and Outpatient's clinics, At Main Tanta University Hospital. Sample, The sample of this study consisted of: All available nurses working in the previously mentioned settings, and purposive sample of 30adult patients undergoing ureter stent surgery. Tools: four tools were used for data collection as following Tool (I) Structured Interview Questionnaire that was comprised of two parts; Part (1) was Nurses' Socio-Demographic Characteristic. Part (2); Nurse's Knowledge Assessment Sheet. Tool (II): Observation Checklist for Nurse's Performance; Tool (III): Patient Bio Socio-Demographic Data; It was comprised of two parts; Part (1) Socio-Demographic Characteristics of the Patient; Part (2) Clinical Assessment Data of the Patient. Tool (IV): Ureter Stent Symptoms Questionnaire (USSQ) aimed to evaluate patient complications. Results: the present study revealed that, the majority of the studied nurses were poor level of knowledge and un satisfactory practice related to ureter stent surgery pre implementation of educational intervention which has been improved immediately post implementation of educational intervention. Furthermore the frequency of studied patients complications were decreased post- implementation of educational intervention. Conclusion there were a significant enhancement in nurse's knowledge and clinical practice regarding ureter stent surgery after implementing educational intervention related to ureter stent surgery. Recommendation Encouraging continuous in service educational interventions in providing nursing care of patient with ureter stent surgery.