Background: Venous thromboembolism, which involves deep vein thrombosis and
pulmonary embolism, is a serious complication that doubles the risk of morbidity and
mortality after major abdominal and pelvic surgery. Aim: To evaluate the effect of Nursing
led intervention regarding prevention of Venous Thromboembolism among women with
gynaecological tumour undergoing major abdomino-pelvic surgery. Design: This study
utilized a quasi-experimental design. Setting: This study conducted at the gynecological
department and outpatient clinic at Fayoum University Hospital and General Hospital
Fayoum, Egypt. Sample: A purposive sample of 100 women divided randomly into two
groups, 50 women for each groups. Tools of data collection: Three tools were utilized in
this study including an interview scheduled questionnaire, Deep vein thrombosis risk factors
assessment sheet, and deep vein thrombosis assessment sheet. Results: the percentage of
good knowledge regarding VTE were significantly increased in post- test than pre -test
among study group (2.0% pretest vs. 100.0% posttest) compared to control group (0.0%
pretest vs. 4.0% posttest) p= 0.000., also after the implementation of the program the
percentage of good compliance level with VTE preventive measures were significantly
improved by all of the study group (100.0% ) who attained a good level of compliance
compared to control group (40.0%) (p=0.000). In addition; there were one new case of PE
among the control group and 2 cases with DVT compared to no cases reported in study
group with a highly statistical significant difference P= 0.000. Conclusion: Women with
gynaecological tumor who undergoing major abdomino-pelvic surgery who exposed to
nurse led intervention program were not exposed to deep vein thrombosis than those who
exposed to routine hospital only. Recommendations: Nursing led intervention should be
added as an essential part of routine perioperative care for all major gynaecological
operation.