Decubitus ulcers are important health problems and one of the maintrials that health
organization facingevery day. Now a day various innovative modality of wound
treatmenthave been endorsed including wound care. Recently, application of topical insulin
helpsin healing ofdecubitus ulcers. Therefore, the aim of this study was to investigate the
efficacy of applying topical insulin therapy in healing processof decubitus ulcers in
immobilized patients.Design: ARandomized control trial research design was conducted in
Neurological and Medical Departments at Alexandria Main University Hospital. Subjects:
this study composed of 60 patients divided into two equal groups, study group who receive
topical insulin dressing and control group who receive routine hospital dressing. Results,
indicates significant improvement in decubitus ulcers healing forthe study group compared
control to their where p value (˂0.05)Conclusion, topical application of insulin has a very
powerful effect in healing process for decubitus ulcers. Recommendation: in service
education program for nurses working in neurological and medical departments