COVID-19 is one of the major pathogens that triggered a great public health
threat. The study aimed to compare the level of knowledge and attitude of the
nursing students about COVID-19 before and after implementation of an
intervention educational guideline at four nursing faculties selected to represent
different geographical regions of Egypt; namely Cairo, Mansoura, Port Said, and
Beni- Suef Nursing faculties. Through using a quasi-experimental study of 1550
nursing students. A self-administered questionnaire was used composing of three
parts; Nursing students' personal characteristics, Knowledge about COVID-19,
and attitude towards the COVID-19 scale. The findings showed that the mean
difference in scores of both knowledge and attitude was significantly higher in
older students, urban residence, living in students' hostile and achieving grade C
in the past year.However, the mean difference in knowledge score is
significantly higher in students affiliated to Mansoura University compared to
those of Port Said University. The present study concluded a good knowledge
and a high attitude among the targeted students towards COVID-19 post
implementation of the guidelines.