Back ground: Bullying is commonplace among students with disabilities. Children with special needs expose to peer victimization twice to three times frequently more than the general population, and the rate of bullying increases for those with observable disabilities. Adolescent girls with visual impairment become frequently the targets of bullying. Aim to evaluate the effect of audio- drama nursing intervention on bullying among adolescent girls with visual impairment. Design: A quasi experimental design (pre/post-test) was utilized. Setting: Al Nour School for visual impairment children, Shebin El-kom, Menoufia, Egypt. Sample: A purposive sample of forty visually impaired adolescent girls. Instruments: Four tools were used for data collection; I: Structured interviewing questionnaire which consisted of two parts; first part to assess socio-demographic data; second part to assess previous exposure to bullying. II: Adolescent girl's knowledge about bullying III: Adolescent bullying scale: IV: Rosenberg's global self-esteem scale. Results: the findings of current study showed that 70% of adolescent girls had good knowledge on post intervention compared to 70% of them had poor knowledge on pre intervention. Mean of total score of adolescent girls' problems with bullying was decreased on post intervention (16.47 ± 4.90) compared to (27.40 ± 4.33) on pre intervention. Also, mean total score of methods of dealing with bullying was improved on post intervention (8.025 ±1.48) compared to pre intervention (4.600 ±2.39). In addition, 77.5% of the studied students had high self-esteem on post intervention compared to 20.0% on pre intervention.Conclusion: The audio- drama nursing interventions were successful in improving the visually impaired adolescent girls' knowledge and dealing effectively regarding bullying. They also have significant effect on self-esteem.Recommendation: Raising awareness of visually impaired adolescent girls regarding bullying in various settings by further educational programs particularly for school girls with visual impairments.