Aim of the study: The aim of the study was to assess risk factors of periodontitis associated pregnancy and its effect on pregnancy outcome. Subjects and Methods: This was an exploratory descriptive study which was conducted among (91) fulfilled criteria (freedom from any medical, gynecological and obstetrical history) pregnant women attending the antenatal care unit in Alwaleedia Health Centre –Asyut -Egypt from August 2017 to February 2018. Data collection tools were a 'Structured Interviewing questionnaire and an oral examination checklist conducted to a purposive sample and data were analyzed using SPSS software, descriptive statistics and chi-square test. Result: The present study showed that various levels of periodontal disease among pregnant women were associated with bio sociodemographic characteristics such as age, economic status and educational level, gestational age, obesity, previous dental history and lack of dental hygienic measures. Meanwhile, there was a significant relationship between periodontal disease and adverse pregnancy outcomes (p<0.001). Conclusion: Age, economic status and educational level, gestational age, obesity, previous dental history and lack of dental hygienic measures are risk factors of periodontal diseases during pregnancy. Periodontitis associated pregnancy have adverse effect on pregnancy outcome. Recommendations: Activating the role of the maternity health nurse in branches of Obstetrics and antenatal clinics to enhance pregnant women's knowledge &attitude regarding oral health risks during pregnancy to ensure early disease detection and adverse outcomes prevention.