Background: Children with Autism Spectrum Disorder (ASD) have problems in the social interaction, communication skills, repetitive and stereotyped patterns of behaviors, and interests of activities across multiple contexts. Aim: this study aimed to assess the effect of selected play activities along with music therapy on social and stereotype behaviors among school age children with autism. Design: one group pre and post quasi-experimental design was used in this study. Sample: A purposive sample of thirty school age children diagnosed with autism. Setting: this study was conducted at Center for Social and Preventive Medicine (Child Psychiatry Outpatient Clinic) Cairo University Hospital. Data collection Tools: data were collected using three tools: Socio-demographic and Medical Data Sheet, Autism Social Skills Profile (ASSP), Stereotyped Behavior Scale (SBS). Results: more than half of the studied sample (56.7%) suffers from low level of social skills interaction pre-intervention as compared to 3.3% post intervention, statistically significant difference were found between social skills and stereotype behaviors pre and post intervention. The study recommended that, music and play therapy should be integrated in treatment programs for those children.