Hepatitis C virus is an important public health problem in both developing and developed
countries. Egypt has the highest prevalence of hepatitis C in the world. The study aimed to
assess the quality of life of hepatitis "C" patients undergoing interferon therapy in Benha City.
Research design: Descriptive research design was utilized to conduct this study. Setting: the
study was conducted at Hepatic Center at Fever Hospital in Benha City. The sample: Simple
random sample was used to choose 150 patients with chronic hepatitis C receiving interferon
therapy regardless their age &sex. Tools of data collectionI: A structured interviewing
questionnaire to assess patients' socio-demographic characteristics, present and past medical
history, Knowledge and practices related to chronic hepatitis C and interferon therapy. II: Quality
of life scale of hepatitis "C" patient's undergoing interferon therapy. Results: Hepatitis C was
more prevalent among males than females in the study sample, 74.0% of the studied sample were
males, 44.7% of patients had good total knowledge score about hepatitis C and interferon therapy,
76% had satisfactory total practices, 21.3% of them had good total quality of life score.
Conclusion: There was statistically significant difference in relation to marital status among
studied sample, there was no statistically significant difference between patients' total practices
and their total quality of life. Also there was no statistically significant difference between
patients' total knowledge and their total practices. Recommendations: Health education program
should be conducted at Hepatic Center to improve knowledge, practice and their quality of life of
hepatitis C patients.