Aim of the study: was to assess the quality of life among children suffering from chronic
kidney disease. Research design: A descriptive design was used in this study. Setting: This study
was conducted in the pediatric nephrology clinic, and the pediatric conservative nephrology clinic
of the pediatric dialysis unit at Ain Shams University Children Hospital. Sampling: A Purposive
sample, 164 children with their mothers. The criteria of sample: - the inclusion criteria included
all available children with age 4-12 years old, both gender and their mothers. Tools of data
collection: The first tool:- A questionnaire tool included the following Socio-demographic data of
children, Socio-demographic data of mothers and fathers, environmental assessment for children
living in. Assessment of mother's knowledge about CKD, and assessment of mother's practice
related to children health needs and problem related to CKD by mother's role towards the needs
and problem. The second tool: - Quality of life inventory scale was constructed to assess level of
quality of life for children with chronic kidney disease. The third tool: Children medical record to
assess health status of children. Results: As regards characteristics of the studied children it was
found that 41.5% of the studied children were in age from 4<6 year, and 59.8% of the studied
children were males, and that 68.9% of the studied sample had a positive level of physical domain
of quality of life, that there was a highly statistical significant relation (p<0.001) between total
knowledge and total QOL. Conclusion: - In conclusion the finding of this study revealed that
41.5% of the studied t of children age was ranged from 4<6years, Indeed less than half of mothers
had unsatisfactory total knowledge, and uncorrected total practice. Most of the children were low
weight, and the majority were suffering from loss of appetite. There was statistical significant
relation between mothers' age, educational level, and their total practice. Represent that there was
a highly statistical significant relation (P<0.001) between total knowledge and total QOL. And
clarifies that was highly statistical significant relation between total knowledge and total practice.
Recommendations: Educational training programs to children with CKD and their mother to update their knowledge and practice. Effort should be made to reduce the CKD complications
among children through adopting a national strategies and plans of CKD prevention, care and
control.