Multiple sclerosis (MS) is the most common chronic, non-traumatic neurological disorder
afflicting young people during their peak productive ages. It affects approximately 2.5 million
people worldwide, and 1.4% of all Neurology cases in Egypt. Once the disease has developed, it
continues lifelong, and there is still no cure. The course of the disease can be relapsing–remitting
which diminish quality of life (QOL) by interfering with the ability to work, pursue leisure
activities, and carry on usual life roles. This study was aiming to assess the effect of psychosocial
nursing intervention on quality of life of patient with multiple sclerosis. It was conducted on 50
cases with MS in El-Demerdash day care unit. Data were collected using: 1) Interviewing
questionnaire containing the following parts A) Socio-demographic sheet. B) History of illness,
C) Patient's knowledge regarding multiple sclerosis. 2) Multiple Sclerosis Quality Of Life
(MSQOL-54) instrument. The result of this study showed that, there are highly statistically
significant differences were found between pre- and post- intervention as regard knowledge about
disease of patient with multiple sclerosis (P= .000). Additionally, there are highly statistically
significant difference were found between pre- and post- intervention as regard physical health
composite and mental health composite of patient with multiple sclerosis (P= .000) respectively.
As well as, there is highly statistically significant difference was found between pre-and postintervention as regard total overall quality of life of patient with multiple sclerosis, (P= .002).
Results concluded that the implementation of psychosocial nursing intervention had a positive
effect on quality of life of patient with multiple sclerosis. Based on the results, it is
recommended to incorporate non-drug therapy (psychosocial intervention) along with
pharmacological therapies in MS management to improve quality of life of patients with MS.