Introduction: Nursing staff has an important role in understanding and apply the six international patient children safety goals to minimized hazards and errors. The Aim of the study: This study aimed to assess the dimensional application of nursing for international safety goals in hospitalized children. Research Design: A descriptive design was utilize in this study. Setting: it was conducted at Pediatric outpatient clinics in Children Hospital affiliated to Ain Shams University Hospitals and and Health Insurance Hospital in Nasr city. The subjects: The subject of this study was convenient sample composed of 100 nurses working at the previously mentioned settings regardless their experiences, level of education, position, or age. Tools of data collection: First tool: A structured Interviewing Sheet: this tool was designed by the researcher and written in simple Arabic language based on scientific literature review to gather data and knowledge about dimensional of children international safety goals in pediatric department at previously mentioned settings. Results: There was statistical significant difference between years of experience of the studied nurses and their knowledge and practices regarding to child patient safety. Conclusion: In the light of the study findings, it might be concluded that, more than half of the studied nurses had poor knowledge and unsatisfactory practices regarding the levels of the dimensional application of international safety goals for children in hospital. Meanwhile the factors contributing as obstacles for dimensional application of international safety goals for children in hospital were observed in the positive relation between the years of experiences of the studied sample and its relation with their level of knowledge and practices. Recommendation: Establishing the system of application the international safety goals for children in hospital and emphasize the important of application the international safety goals for children in hospital in nursing.