Background: The introduction of sovaldi combination therapy marked the beginning
of a new era in HCV treatment in Egypt, which is highly-effective with cure rate over 90%as
a part of MOHP efforts to eliminate the morbidity and mortality resulting from its prognosis
and to control the viral hepatitis epidemic. Aim of the study: was to assess knowledge,
practice and satisfaction of clients with hepatitis C virus regarding sovaldi therapy. Design:
descriptive research design was utilized to carry out this study. Setting: The present study
was conducted at the liver center in Banha City. Sample: purposive sample including 290
clients with hepatitis C virus at the liver center in Banha City. Tools: an interviewing
questionnaire was used, it divided into four main parts: Part 1: Socio-demographic
characteristics and medical data, Part 2: client knowledge regarding sovaldi therapy, Part 3:
client practices regarding sovaldi therapy, Part 4: client satisfaction regarding the provided
care. Results: this study indicated that, mean age for study subjects was 35.23±11.58, 67.6%
of them were male, 71.3% of the study subjects had unsatisfactory level of knowledge
regarding HCV and sovaldi combination therapy, 31.4% of the study subjects had
satisfactory practices regarding sovaldi combination therapy; 69.7% were unsatisfied from
the quality of care provided. Conclusion: there are significant association between the
clients total knowledge score and educational qualification, occupation and income, there
was a highly statistical significance association between total practice score and their
educational qualification and their age, there are highly statistical significance association
between total satisfaction score and their income. Recommendation: Based on this finding,
the investigator recommended to carry out health education sessions to the clients receiving
sovaldi therapy regarding: their practices toward sovaldi administration, proper nutrition, the
restricted medication during treatment and about the possibility of re infection.