Aim: This study was to explore barriers that facing student nurses during their practical training at obstetrics and gynecological department. Setting: The study was conducted at the Obstetrical and Gynecological Department of the Faculty of Nursing at Benha University. Design: A descriptive design was utilized. Sampling: A convenient sample included (180) student nurses. Tools: Two tools were used, the first tool was interviewing questionnaire sheet for assessing the general characteristics of students and assessment of barriers which facing the student during their practical training. The second sheet was modified student satisfaction questionnaire. Results: Many barriers faced students during their practical training and (72.2%) of students were unsatisfied while (10.6%) of students were satisfied and (17.2%) were satisfied to some extent and there was highly negative significant correlation between total barrier score and total satisfaction score (p >0.001). Conclusion: Many barriers faced the students during their practical training at the lab, the hospital and during the application of skills and nearly to third quarters of the total of students weren't satisfied with the practical training, there was highly negative significant correlation between total barrier score and total satisfaction score. Recommendation: Continuous evaluation of students' opinion regarding the teaching process, curriculum, their needs and satisfaction as a part of developmental plans of the quality of