Cerebral palsy (CP) is a permanent disorder of posture and movement resulting from brain damage occurring in the baby or young child. Cerebral palsy is a term used to describe a collection of disorders caused by abnormal brain development or damage to the brain that occurs around the time of birth or early in life. This study aimed to evaluate the intervention program for mothers regarding dependency level of their children with CP. Setting the current data was Neurology out- patient clinic at pediatric hospital Ain Shams University. Sample, The study was conducted on one hundred and twenty four mothers who have been selected for the program pre, post, and after 3 month later. Tools: Two tools for data collection, tool (I) An interviewing questionnaire sheet (II) Child‟s activities of daily living assessment. Results of this study showed that the main age of mothers was 37.6 ± 0.6 years and noticeable improvement in the mothers‟ knowledge and practice and dependency level of their children were detected after implementation of intervention program compared to pre and 3 month after program implementation. So, this study concluded that intervention program affected positively regarding caring of mothers regarding dependency level of their children with cerebral palsywhich indicate justification of the study hypotheses. this study recommended that Educational sessions should be provided for mothers of cerebral palsy children about care of their children, as well as, community resources from whom they may seek assistance and support to fulfill with all dependency level of their CP child.