Background: Schizophrenia is a chronic illness that is often characterized by periodic
relapses and incomplete remissions. Aim of the study: This study aimed to develop psycho
educational program for prevention of relapse among the patients with schizophrenia and evaluate
the effectiveness of the psycho educational program on the prevention of relapse among the
schizophrenic patients. Methods: This study used a convenience sample of 60 patients with
schizophrenia(15 female and 45 male) at Psychiatric Mental Health Hospital at Benha City. Tools
for data were collected by using two tools: Structured interview questionnaire sheet concerning
knowledge about schizophrenia and relapse and Drug Attitude scale (DAI-30). Results the
findings demonstrated that the studied patients with schizophrenia had severe lack of knowledge
about schizophrenia and relapse and non-compliant with medication before program
implementation. There is a highly positive correlation between knowledge about relapse and
schizophrenia and attitude toward drug compliance. Conclusion: Psycho education is an effective
tool in improving patient's knowledge about schizophrenia and relapse. The study recommended
that psycho-educational sessions need to be involved in the daily patient`s treatment program of
the patients with schizophrenia even 10 minutes per day, and must be provided to all psychiatric
patients voluntary and involuntary admitted, in psychiatric and in general hospitals.