This study aims to determine the level of social competence among social workers and its relation to the outcome of professional practice. In light of this, the researchers adopted a social survey methodology. The social competence scale for social workers and the professional outcome scale applied to the study sample of 146 social workers who are working in the field of care for special groups in Cairo Governorate. The results of the study showed that the level of social competence of social workers in the care of special groups is medium with arithmetic mean equal to 3.51. As for the level of professional outcome for social work practice among social workers (sample study), it is medium the arithmetic mean of (2.28). It means, whenever the social competence in the sample of research from social workers increases, the professional outcome of the social work practice in the care of special groups increases. As well as whenever the social competence of social workers decreased, the professional outcome of the social work practice decreased. Thus, the findings are consistent with the research hypotheses. The study found that social competence among social workers has a role in raising the outcome of professional practice in the care of special groups. This study is one of the rare studies that link the variable dimensions of social competence among social workers and the outcome of professional practice.