This study aimed to determine the relationship between social media and social relations among university students, users and non-users of social media.  It also aimed to Identify indicators for social workers to enable them to work with to support the social relationships for university students, users of social media, from social and natural science disciplines.  The study population comprised the whole student body of HelwanUniversity with all its faculties.  The total sample of the research was 210 students, where 95 students were from social science disciplines (specifically Faculty of Social Work and Faculty of Arts), and 115 students were from natural science disciplines (specifically Faculty of Pharmacy and Faculty of Sciences). The study concluded that there are differences between the social media user and non-user students from social science disciplines, and no differences between user and non-user students from natural science disciplines on the social relations scale.  However, there are differences between the mean scores of social media non-user students from social science disciplines and those from natural science disciplines on the social relations scale