Background and study aim: Hepatocellular‏ ‏Carcinoma ( HCC) is regarded as one of the most ‎widespread leading causes of mortality annually . The most ‎frequent risk factors for HCC are chronic viral hepatitis  infection‎‎, which account for 80% of all HCC cases globally. This study ‎aims to highlight epidemiological, clinical, laboratory and ‎radiological characteristics of HCC in patients attending ‎Tropical Medicine Department‎‎.
Patients and Methods: A Retrospective study was conducted on medical records of all ‎patients attending Tropical Medicine Department to determine ‎the socio demographic, laboratory, clinical and radiological ‎characteristics of HCC.‎
Results:‎715 patients with HCC were included in this study. The mean ‎age of HCC onset was (59.76±8.14), 68% were males, 32 % ‎were females, 39.7 % were diabetic ,  Two thirds of the patients ‎were Child-Pugh A (67%), the remaining third were child B ( ‎28.2%) and child C (4.9%).  9.5% were jaundiced, 20% were ‎ascitic, 74.8% had splenomegaly, 8.7% had malignant PVT ‎while 0.4 % had Benign PVT, AFP was > 400 in 16.2 %  of ‎patients. 19.8 % had received HCV treatment, 67 % were active ‎HCV‎‎‎‎‎‎‎.
Conclusion: Hepatocellular carcinoma is predominant in older- male patients ‎with chronic hepatitis C not receiving treatment, and  have ‎diabetes mellitus‎‎‎‎‎‎‎.