Background and study aim: One of the observed pathological changes in corona virus disease 2019 (COVID-19) is imbalance ‎of sodium homeostasis‎‎‎.We wanted to look at the imbalance in blood sodium values in COVID-19 patients and detect ‎whether dysnatremia affects the prognosis COVID-19 patients who were admitted with extreme ‎acute respiratory disorder coronavirus2 (SARS-COV2)‎.
Patients and Methods: ‎‎‎ A retrospective study on 163 patients with confirmed COVID-19. Clinical information was ‎obtained from individuals' medical records, as well as electrolyte values. The authors addressed the ‎correlations between sodium serum levels in COVID-19 patients, as well as the clinical ‎characteristics, implications, and underlying severity and mortality‎‎.‎
Results: From a sum of 163 COVID-19, 71 patients had hyponatremia (under 135 mmol/L) and   9 patients ‎had hypernatremia (over 145 mmol/L). Patients with sodium balance problems had more severe ‎illness than those with normonatremia. A total of 53.5 percent of hyponatremia patients and 11.1 ‎percent of hypernatremia patients had a mild or moderate condition, with lower ratios than ‎normonatremia patients (38.5 percent). However, a total of 47.5 percent of hyponatremia patients ‎and 88.9% of hypernatremia patients had serious or critical diseases with higher ratios than ‎normonatremia patients (61.5 percent ). Patients with dysnatremia had a greater death rate than ‎those with normonatremia‎‎‎.
Conclusion: Hypernatremia is linked to an elevated risk of serious illness and mortality in the hospital. In patients with SARS-COV2 infection, hypernatermia was linked to a greater risk of mortality ‎‎‎.