Beta
ManageSearchChatDiscover
255825

Prevalence of Gastro-Esophageal Reflux Disease in Patients with ‎Interstitial Lung Disease: A Case Control Study in Egyptian Patients

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Gastroenetrology

Abstract

Background and study aims: It is unknown whether the gastro-esophageal reflux disease (GERD) is a cause or ‎consequence of interstitial lung disease (ILD). This study aimed to determine the  ‎prevalence of gastro-esophageal reflux disease in patients with interstitial  lung disease ‎and to show the correlation  between them‎‎‎‎.‎
Patients and Methods: ‎‎‎ From April 2020 to May 2022, we have prospectively analyzed the data of 210 patients ‎with interstitial lung disease who had GERD according to Hull Airway Reflux ‎questionnaire and Los Anglos classification of GERD in upper gastrointestinal (GI) ‎endoscopy and 210 controls without any respiratory disease who performed upper GI ‎endoscopy for any cause. We used binary logistic regression analysis to determine the ‎factors associated with ILD or GERD among the studied participants‎‎.‎
Results: In the study sample, the prevalence of GERD was significant among ILD patients ‎‎(52.4%) compared to controls (38.6%) (p=0.004).Binary logistic regression analysis ‎revealed that smoking (OR=3.98, 95%CI: 2.44-6.50), GERD (OR=1.59, 95%CI: 1.04-‎‎2.46), forced  vital capacity (OR=0.95, 95%CI: 0.91-0.99) were the main predictors of ‎ILD, while on analysis of the predictors of GERD, ILD (OR=1.67, 95%CI: 1.10-2.53) ‎and  FEF25-75 (OR= 1.06, 95%CI: 1.03-1.09) were the most significant predictors‎‎‎‎.
Conclusion: The prevalence of GERD in the patients with interstitial lung disease was high and may ‎be an important contributor to the development of interstitial lung diseases‎ ‎‎‎.

DOI

10.21608/aeji.2022.148084.1236

Keywords

Gastro-esophageal reflux, Interstitial Lung Disease, prevalence, upper gastrointestinal endoscopy

Authors

First Name

Ahmed

Last Name

Teima

MiddleName

-

Affiliation

Department of Tropical Medicine, Faculty of Medicine, Menoufia University, Menoufia, ‎Egypt.‎

Email

dr.ahmed_zaid@yahoo.com

City

-

Orcid

-

First Name

Randa

Last Name

Seddik

MiddleName

M

Affiliation

Department of Tropical Medicine, Faculty of Medicine, Menoufia University, Menoufia, ‎Egypt.‎

Email

randa.sedeek@med.menofia.edu.eg

City

Shebin Elkom

Orcid

0000-0001-9389-7635

First Name

Lamiaa

Last Name

Mohammed

MiddleName

I

Affiliation

Shebin Elkom Chest Hospital, Menoufia, Egypt.‎

Email

dr.lamia_ibrahim@yahoo.com

City

-

Orcid

-

First Name

Hanaa

Last Name

Eid

MiddleName

A

Affiliation

Department of Chest, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Email

hanaaeid1234@gmail.com

City

-

Orcid

-

First Name

Zeinb

Last Name

Kasemy

MiddleName

A

Affiliation

Department of Public Health and Community Medicine, Faculty of Medicine, Menoufia ‎University, Menoufia, Egypt.‎

Email

zeinabkasemy@gmail.com

City

-

Orcid

-

First Name

Nouran

Last Name

Aborlkhair

MiddleName

T

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Menoufia University, Menoufia, ‎Egypt.‎

Email

noran.aboelkhair@med.menofia.edu.eg

City

-

Orcid

-

First Name

Mahmoud

Last Name

Moawad

MiddleName

M

Affiliation

Department of Clinical Radiology, Faculty of Medicine, Menoufia University, Menoufia, ‎Egypt.‎

Email

dr.m.m.a.moawad@gmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Abdel-Samiee

MiddleName

-

Affiliation

Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia ‎University, Menoufia, Egypt.‎

Email

drmohammed100@yahoo.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Edress

MiddleName

-

Affiliation

Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia ‎University, Menoufia, Egypt.‎

Email

edrees.ahmed@yahoo.com

City

-

Orcid

-

First Name

Housam

Last Name

Helmy

MiddleName

A

Affiliation

Department of Hepatology and Gastroenterology, National Liver Institute, Menoufia ‎University, Menoufia, Egypt.‎

Email

drh.bary2006@gmail.com

City

-

Orcid

-

First Name

Ashraf

Last Name

Eid

MiddleName

M

Affiliation

Department of Gastroenterology, Hepatology and Infectious Diseases, Shebin El-‎Kom Teaching Hospital, Shebin El-Kom, Egypt.‎

Email

eid.ashraf74@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Abdelhamed

MiddleName

R

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, ‎Egypt.‎

Email

dr.dodo500@gmail.com

City

-

Orcid

-

First Name

Amany

Last Name

Amer

MiddleName

A

Affiliation

Department of Tropical Medicine, Faculty of Medicine, Menoufia University, Menoufia, ‎Egypt.‎

Email

amany.abbas630@med.menofia.edu.eg

City

-

Orcid

-

Volume

12

Article Issue

3

Related Issue

36292

Issue Date

2022-09-01

Receive Date

2022-07-02

Publish Date

2022-09-01

Page Start

259

Page End

268

Print ISSN

2090-7613

Online ISSN

2090-7184

Article File

AEJI_Volume 12_Issue 3_Pages 259-268.pdf

PDF . 378.1kB

Link

https://aeji.journals.ekb.eg/article_255825.html

Detail API

https://aeji.journals.ekb.eg/service?article_code=255825

Order

10

Type

Original Article

Type Code

616

Publication Type

Journal

Publication Title

Afro-Egyptian Journal of Infectious and Endemic Diseases

Publication Link

https://aeji.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023