Background and study aims: The prevalence of gastro-esophageal varices (GOVs) in cirrhotic patients ranges from 40-80%.The most serious complication of cirrhosis is variceal hemorrhage since it has a mortality rate of 17-57%. Endoscopy is the standard test to detect GOVs. This study aimed at the evaluation of liver stiffness (LS)-spleen size-to-platelet count ratio score (LSPS) as a risk score for the prediction of esophageal varices (OVs) in patients with compensated liver cirrhosis.
Patients and Method: ‎This study included 51 patients with compensated cirrhosis. Screening ‎upper endoscopy was done for the detection of OVs. They were also ‎evaluated by transient elastography and laboratory tests, then divided ‎according to the presence or absence of OVs. We compared both groups based on ‎LSPS and platelet count splenic diameter ratio (PSR)‎.‎
Results: the LSPS ratio has sensitivity 87.88% and specificity 88.89% for prediction of ‎OVs. Regarding Platelet count /Splenic diameter ratio the cut off value for ‎the prediction of OV was 909.09 with sensitivity 87.9% and specificity ‎‎88.9%‎‎‎.
Conclusion: PSR and LSPS provided good diagnostic tool for the prediction of ‎esophageal varices in compensated cirrhotic patients.