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Prevalence and associated factors associated with Uropathogenic Escherichia coli isolates from catheterized persons at Ilorin Tertiary Hospital, Nigeria

Article

Last updated: 22 Jan 2023

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Subjects

-

Tags

Infectious diseases

Abstract

Background and study aim: Urinary tract infection (UTI) is among the most common complications of catheterized persons in hospital settings especially, those caused by extended spectrum beta lactamase (ESBL) and biofilm producing Escherichia coli.This hospital based, cross sectional study was carried out to determine the prevalence and associated factors associated with Uropathogenic Escherichia coli (UPEC) isolates from catheterized persons (inpatients and outpatients) attending Ilorin Tertiary hospital, Nigeria
Materials and Methods: Between 2nd April and 30th June 2016, urine samples from 113 catheterized inpatient and outpatients were evaluated. Female subjects accounted for 47(41.6%) of the study population. Standard microbiological methods and Analytical Profile Index (API) 20E system were used for the isolation and identification of UPEC, respectively. Tissue culture plate (TCP) technique was used to demonstrate biofilm production potentials.
Results: The prevalence of catheter associated urinary tract infection (CA-UTI) in this study was 70.8% most of which are Gram negative bacilli belonging to the Enterobacteriaceae family with Escherichia coli 44(55.0%) being the most predominant pathogen.Extended spectrum beta lactamase (ESBL) E coli in this study was 27.2% of which all (100%) were strong biofilm producers. Female subjects had relatively higher prevalence of UPEC isolates, 29 (65.9%) than the male counterparts. Whereas, the highest cases of UPEC was in 61-70 years age group, 29.5%. There was significant association between UPEC and age and gender of subjects (p<0.05).
Conclusion: Findings from this study shows that E. coli is still the most common uropathogenic bacteria isolate in catheterized persons. Biofilm production confers some degree of ESBL production and antibiotic resistance.

DOI

10.21608/aeji.2019.11367.1019

Keywords

Antimicrobial resistance, risk factors, ESBL, Biofilm

Authors

First Name

Dele

Last Name

Amadu

MiddleName

Ohinoyi

Affiliation

Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria

Email

deleohi@yahoo.com

City

-

Orcid

-

First Name

Charles

Last Name

Nwabuisi

MiddleName

-

Affiliation

Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria

Email

-

City

-

Orcid

-

First Name

Thairu

Last Name

Yunusa

MiddleName

-

Affiliation

Department of Medical Microbiology and Parasitology, University of Abuja, Nigeria

Email

-

City

-

Orcid

-

First Name

Idris

Last Name

Nasir

MiddleName

Abdullahi

Affiliation

Department of Medical Laboratory Science, College of Medical Sciences, Ahmadu Bello University, Zaria

Email

eedris888@yahoo.com

City

Abuja

Orcid

0000-0002-5511-1272

First Name

Janet Mosunmola

Last Name

Oladejo

MiddleName

-

Affiliation

Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria

Email

janetmmosunmla@gmail.com

City

-

Orcid

-

First Name

Ezeikel

Last Name

Seibu

MiddleName

-

Affiliation

Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria

Email

ezeikelss@yahoo.com

City

-

Orcid

-

First Name

Abayomi

Last Name

Fadeyi

MiddleName

-

Affiliation

Department of Medical Microbiology and Parasitology, University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria

Email

abayumm@yahoo.com

City

-

Orcid

-

First Name

Yahaya

Last Name

Usman

MiddleName

-

Affiliation

Department of Medical Laboratory Science Ahmadu Bello University, Zaria, Nigeria

Email

elyahyyy@yahoo.co.uk

City

-

Orcid

-

First Name

Dorcas

Last Name

Aliyu

MiddleName

-

Affiliation

Department of Medical Laboratory Services. Family Health International 360, Abuja, Nigeria

Email

doxyyhali@yahoo.com

City

-

Orcid

-

Volume

9

Article Issue

2

Related Issue

5647

Issue Date

2019-06-01

Receive Date

2019-03-31

Publish Date

2019-06-01

Page Start

119

Page End

128

Print ISSN

2090-7613

Online ISSN

2090-7184

Article File

AEJI_Volume 9_Issue 2_Pages 119-128.pdf

PDF . 437.2kB

Link

https://aeji.journals.ekb.eg/article_33910.html

Detail API

https://aeji.journals.ekb.eg/service?article_code=33910

Order

2

Type

Original Article

Type Code

616

Publication Type

Journal

Publication Title

Afro-Egyptian Journal of Infectious and Endemic Diseases

Publication Link

https://aeji.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023