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18254

Pneumocystis jiroveci: Epidemiology and diagnosis

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Infectious diseases

Abstract

The Pneumocystis organism was initially described in 1909 by Chagas. Pneumocystis jiroveci is an uncommon opportunistic organism, which induces a severe and mostly fatal pneumonia in immunocompromised people. Pneumocystosis comes from reactivation of latent infection acquired while childhood or active acquisition while immunosuppression state. The epidemiology of Pneumocystis pneumonia (PCP) has changed considerably through the course of the HIV/AIDS epidemic. The establishments of PCP prophylaxis in 1989 and effective combination antiretroviral therapy in 1996, have resulted in substantial reduces in the incidence of PCP. Due to the insufficient specificity of clinical symptoms as well as the possibility of toxicity with therapy, the affirmation of PCP is important details for correct patient management. The traditional method for diagnosis of PCP depends on the microscopic visualization of organisms in respiratory samples. PCR diagnosis of P. jiroveci was introduced experimentally in 1990. Molecular methods, could detect P jirovecii DNA in respiratory samples from patients without clinically apparent PCP. In this review both epidemiology and diagnosis of Pneumocystis jiroveci will be discussed.

DOI

10.21608/aeji.2013.18254

Keywords

Pneumocystis jiroveci, Pneumocystis pneumonia, immunodeficiency

Authors

First Name

Zineb

Last Name

Tlamçani

MiddleName

-

Affiliation

Laboratory of Peripheral Hospital Center, Taroudant, Morocco

Email

tzineb@hotmail.fr

City

-

Orcid

-

First Name

Mohammed

Last Name

Er-Ram

MiddleName

-

Affiliation

Department of Parasitology, Faculty of Medicine and Pharmacy of Fes, Morocco

Email

-

City

-

Orcid

-

Volume

3

Article Issue

4

Related Issue

3785

Issue Date

2013-12-01

Receive Date

2013-12-02

Publish Date

2013-12-10

Page Start

122

Page End

126

Print ISSN

2090-7613

Online ISSN

2090-7184

Article File

AEJI_Volume 3_Issue 4_Pages 122-126.pdf

PDF . 173.3kB

Link

https://aeji.journals.ekb.eg/article_18254.html

Detail API

https://aeji.journals.ekb.eg/service?article_code=18254

Order

3

Type

Review article and meta analysis

Type Code

620

Publication Type

Journal

Publication Title

Afro-Egyptian Journal of Infectious and Endemic Diseases

Publication Link

https://aeji.journals.ekb.eg/

MainTitle

Pneumocystis jiroveci: Epidemiology and diagnosis

Details

Type

Article

Created At

22 Jan 2023