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17831

Rhinocerebral Mucormycosis Presented with Cranial Nerves Deficit

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

Infectious diseases

Abstract

Mucormycosis is a rare opportunistic fungal infection, associated with high mortality, characterized by infarction and necrosis of host tissue. Rhinocerebral mucormycosis (RCM) is the most common clinical variant often associated with poorly controlled diabetes mellitus. The treatment is complex and involves both antifungal and surgery. There is no formal guideline regarding the duration of antifungal, timing and extent of surgical management. We present a case of RCM in a diabetic girl who presented with a 2 weeks history of    left facial  and periorbital swelling associated with left facial numbness and deficit of the fifth and seventh cranial nerves. Diagnosis of RCM was confirmed by histopathological examination of tissue biopsy. She was successfully treated with liposomal amphotericin B and posaconazole, as step-down therapy, along with minimal surgical debridement. We present this case because of the rarity of RCM, calling for prompt initiation of treatment in a suspected case and to present data about therapeutic modality.

DOI

10.21608/aeji.2015.17831

Keywords

Diabetes mellitus, mucormycosis, zygomycosis

Authors

First Name

Maysaa

Last Name

Saeed

MiddleName

Abdallah

Affiliation

Tropical Medicine Department, Faculty of Medicine, Zagazig University, Egypt.

Email

dr.maysaaabdallah@windowslive.com

City

-

Orcid

-

First Name

Tarek

Last Name

Attia

MiddleName

H

Affiliation

Pediatric Department, Faculty of Medicine, Zagazig University, Egypt.

Email

-

City

-

Orcid

-

First Name

Abdullah

Last Name

Al Ghamdi

MiddleName

S

Affiliation

Internal Medicine Department, King Saud Medical City, Kingdom of Saudi Arabia.

Email

-

City

-

Orcid

-

Volume

5

Article Issue

3

Related Issue

3729

Issue Date

2015-09-01

Receive Date

2015-09-02

Publish Date

2015-09-29

Page Start

201

Page End

204

Print ISSN

2090-7613

Online ISSN

2090-7184

Article File

AEJI_Volume 5_Issue 3_Pages 201-204.pdf

PDF . 142.5kB

Link

https://aeji.journals.ekb.eg/article_17831.html

Detail API

https://aeji.journals.ekb.eg/service?article_code=17831

Order

9

Type

Case report

Type Code

622

Publication Type

Journal

Publication Title

Afro-Egyptian Journal of Infectious and Endemic Diseases

Publication Link

https://aeji.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023