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DOI

10.21608/aeji.2015.17823

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Background and study aim: Hepatocellular carcinoma (HCC) is currently the fifth most common solid tumor worldwide and the third leading cause of cancer-related death. Percutaneous ethanol injection (PEI) and radiofrequency ablation (RFA) techniques b, the first group included 72 patients whom had NLR less than 5 and the second group included 64 patients whom had NLR equal or more than 5. Patients underwent PEI or RFA. Clinical assessment, laboratory evaluation and triphasic CT studies were performed to all patients pre-treatment and at 1, 6 and 12 months post treatment. NLR and IL-6 level were performed to all patients pre treatment and at 6 months post treatment. Results: The percentage of complete ablation is highly significantly higher in group I after 1 month but, there is no significant difference between outcome of treatment after 1 year in both groups one year after treatment. Post-procedural IL-6 showed highly significantly lower levels in patients whose focal lesions remain ablated till 1 year than in tho, while NLR did not show significant difference among these groups. Post-prcedural IL-6 levels were highly significantly lower in survived than died cases, while NLR did not show significant differences between both groups at 1 year follow up. There was no significant difference in the post-procedural level of NLR or IL-6 between the group who was treated with ethanol injection and who was treated with, liver profile, hematological profile and diameter of focal HCC and also is a good predictor for short term outcome (1-6 months) and neither pre-procedural or post-procedural NLR are predictors of long term outcome or survival (1 year). Post-procedural IL-6 could be, but also for efficacy of treatment

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5

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3

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3729

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Print ISSN

2090-7613

Online ISSN

2090-7184

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https://aeji.journals.ekb.eg/article_17823.html

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https://aeji.journals.ekb.eg/service?article_code=17823

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Journal

Publication Title

Afro-Egyptian Journal of Infectious and Endemic Diseases

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https://aeji.journals.ekb.eg/