Background and study aim: Hepatic encephalopathy occurs in approximately 30-45% of patients with cirrhosis and 10–50% of patients with transjugular intrahepatic Porto systemic shunt, while minimal hepatic encephalopathy affects approximately 20–60% of patients with liver disease. There are multiple prognostic scores that predict the mortality from chronic liver disease, of which the Child-Pugh score and the Model for End-stage Liver Disease (MELD) score are the most commonly used. The most widely used scale used to evaluate HE is the West-Haven (WH) scale, with scores ranging from 0 to 4. This study is designed to compare Glasgow coma scale to West-Haven scale in prediction of prognosis and survival of patients with hepatic encephalopathy.
Patients and Methods: This study was conducted on 100 patients with liver cirrhosis and overt Hepatic Encephalopathy admitted to The Department of Hepatology, Gastroenterology and Infectious Diseases of Mansoura Health Insurance Hospital, divided into four groups according to the grade of encephalopathy by West-Haven Criteria. 
Results: There was no difference in prediction of survival among the studied patients assessed by GCS, MELD score, uMELD score and Child score (all had the same results).
Conclusion: Glasgow Coma Scale can be a prognostic tool for morbidity and mortality, as well as, follow-up in patients with HE