The morphological surface properties of natural textile materials are important determinants of their usefulness and many of the chemical treatments in use are aimed at modifying these properties. Low temperature plasma has been used as an effective means of modifying the surface properties of natural textile fibers such as wool and cotton. This research work described the screen printing technology and plasma treatment of cotton fabrics. The morphological properties of the plasma treated fabrics were characterized by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). The coloration assessment, wettability, colorfastness and mechanical properties were also evaluated to demonstrate satisfactory results.