Actually, the present current work addresses an innovative approach for benign enhancement of dyeing of cotton fabrics assisted with nanocomposite based on chitosan (Cs), silver nanoparticles (Ag NPs) and clay. The Cs/Ag NPs and Cs/Ag NPs/clay nanocomposites were prepared using UV irradiation and applied on the cotton fabrics by pad-dry-curing method. The blank and treated cotton fabrics were dyed with C.I. Acid Orange 74. The Dye exhaustion, colorimetric analysis as well as fastness properties of the treated fabrics was evaluated. The obtained data proves that the nanocomposite of Cs/Ag NPs/clay is a promising mixture for durable dyeing for cotton fabrics.