Background: Proximal femoral replacement (PFR) is a commonly performed procedure to restore extensive bone defects for different indications with variable reported outcomes. Objective: This retrospective study aimed to assess the functional outcomes and complication rates of PFR with MUTARS or Hipokrat modular femoral mega prosthesis after oncological resections and to highlight the overall patient, limb, and implant survivorship. Patients and methods: A total of 18 patients had PFR after oncological resection. 14 patients had bipolar hemiarthroplasty (BHA) and 4 patients had total hip arthroplasty (THA). At the final follow-up, the patient's functional outcome was assessed by Muscloskeletal Tumor Society score (MSTS) and Toronto Extremity Salvage Score (TESS). Complications were recorded and classified according to the Henderson classification. Results: The mean follow-up was 47.78 months (14-103 months). The mean MSTS and TESS score was 65.7 (range 23-97%) and 81 (range 56-98) respectively. Overall limb, implant, and 5-year patient survival were 94%, 94%, and 66% respectively. The overall complication rate was 39%; 11% instability, 17% periprosthetic fracture, 5.6% infection, and 5.6% local tumor recurrence. Conclusion: PFR is a valid option for reconstruction of huge bone loss after oncological resection of the proximal femur with acceptable longevity, functional outcome, and complication rate with better BHA over THA reconstructive option for stability issues.