277388

Linear Growth of Children with Congenital Adrenal Hyperplasia

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

-

Abstract

Background: Helping children with congenital adrenal hyperplasia (CAH) to reach a normal adult final height is the main goal of treatment. Objective: The aim of the current study is to evaluate the linear growth in kids and teens with congenital adrenal hyperplasia. Patients and methods: A cross sectional study was conducted on 71 Egyptian children with CAH who attended the Diabetes and Endocrine Pediatric Unit at Assiut University Children Hospital, Assiut, Egypt in the period from the start of January 2020 to the end of December 2020. A control group included 71 healthy children matched for age and sex. Results: A total 71 Egyptian children with CAH were recruited; 28 females and 43 males. Of the recruited children, 60 of them were salt loosing type and 11 of them were simple virilizing. The median age at presentation was 5 years and ranged from 1 up to 13 years old. Positive family history was documented in 13 (18.3%) patients. CAH cases were significantly stunted compared to controls (P<0.001). Those presented with salt loosing CAH have significantly lower height and significantly higher BMI as compared to their controls. Conclusions: The multifaceted issue of linear growth in children with CAH is significant. In order to restore normal adult final height in these patients, it is crucial that the condition is appropriately controlled clinically and biochemically through stringent adherence to medicinal therapy as well as continued clinical and laboratory surveillance.  

DOI

10.21608/ejhm.2022.277388

Keywords

Linear growth, Congenital adrenal hyperplasia, Final adult height, Case control study, Assiut University

Authors

First Name

Hanaa Abdel-Lateef

Last Name

Mohammad

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Faisal-AlKhateeb

Last Name

Ahmad

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Ali Hussin Mohamed

Last Name

Hussin

MiddleName

-

Affiliation

-

Email

alihussin@med.aun.edu.eg

City

-

Orcid

-

Volume

89

Article Issue

2

Related Issue

37472

Issue Date

2022-10-01

Receive Date

2022-12-31

Publish Date

2022-10-01

Page Start

7,906

Page End

7,910

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_277388.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=277388

Order

270

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Linear Growth of Children with Congenital Adrenal Hyperplasia

Details

Type

Article

Created At

22 Jan 2023