277376

Bisphenol A in Children with Bronchial Asthma and Its Relation to Body Mass Index

Article

Last updated: 03 Jan 2025

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Abstract

Background: One of the most debilitating diseases in children is bronchial asthma. Little research has been conducted into the relationship between bisphenol A (BPA), a commonly recycled monomer, which is linked to childhood obesity and asthma. Objective: This study's aimed to examine the relationships between paediatric obesity morbidity and bisphenol A (BPA). Subjects and Methods:100 kids between 4 and 10 years were included in this study (25 asthmatics, 25 asthmatics with obesity, 25 obese non-asthmatics, and 25 healthy controls). The diagnosis of asthmatic children was made according to GINA guidelines (Global Initiative for Asthma). The BPA competitive ELISA Kit was used to measure the BPA levels in urine specimens. Looked up for the effect of BPA as a predictor of asthma development in asthmatic children. Additionally, research was done on BPA's potential role in the prediction of childhood obesity. Results: High median total urinary BPA levels (p > 0.001) detected significantly in children with asthma and obesity. Increased levels of BPA were found to be a significant predictor (p = 0.006) in an analysis using multiple logistic regression of asthma predictors. Conclusions: It's possible that BPA played a role in the development of bronchial asthma & obesity, based on the correlation between high BPA levels in urine with asthma diagnostic assessments and children obesity. There is a need for more clinical and biochemical study.  

DOI

10.21608/ejhm.2022.277376

Keywords

Asthma, bisphenol A, Obesity, ELISA

Authors

First Name

Hend M.

Last Name

Soliman

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City

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Orcid

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First Name

Doaa Mohammed Abdou

Last Name

Mostafa

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Dina

Last Name

ezzat

MiddleName

A

Affiliation

clinical pathology depart faculty of medicine kasralainy cairo university

Email

dina.ezzat@kasralainy.edu.eg

City

-

Orcid

0000-0003-3317-4210

First Name

Dina

Last Name

Abdullah

MiddleName

-

Affiliation

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Email

dinaabdullah213@gmail.com

City

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Orcid

-

First Name

Mona

Last Name

Mohsen

MiddleName

-

Affiliation

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Email

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Orcid

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Volume

89

Article Issue

2

Related Issue

37472

Issue Date

2022-10-01

Receive Date

2022-12-31

Publish Date

2022-10-01

Page Start

7,856

Page End

7,864

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_277376.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=277376

Order

263

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Bisphenol A in Children with Bronchial Asthma and Its Relation to Body Mass Index

Details

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Article

Created At

22 Jan 2023