Background: Fluoride, one of the most effective caries-prevention agents, tilts the balance toward health. Fluoride is used for cavity prevention and treatment. Fluoride's demineralization, remineralization, pellicle and plaque prevention, and microbial growth and metabolism inhibition make it anticariogenic. Materials and Methods: Ninety standardized discs of the studied materials were fabricated with dimension of (8mm diameter and 2mm thickness) from cylindrical brass moulds suspended in 8ml polyethylene vial. The amount of fluoride released from the materials was tracked for 30 days, with measurements taken on days 1, 2, 7, 14, and 30. The specimens were separated into three groups at the 30-day mark. The control group's specimens were kept in a container of deionized water. The remaining two sets of specimens were subjected to fluoride-containing oral hygiene products (toothpaste and fluoridated mouthwash). The concentration of fluoride was determined 32 days, 39 days, 46 days, and 53 days after refluoridation. Results: The findings showed that all three fluoride-containing dental materials emitted fluoride, but that each material did so in a different way since it was made up of different parts. The most fluoride was emitted by Fuji IX GP, followed by Ketac nano and Gradia direct X. All of the materials were charged and kept releasing after being subjected to fluoridated toothpaste and mouthwash. All of the materials produced more fluoride after being refluoridated, but GICs released the most. Conclusion: Thus, all three fluoride-containing dental materials produced fluoride in distinct ways owing to their chemical compositions. Possibly. Fluoridated toothpaste and mouthwash activated and released fluoride.