Background: Lichen planus (LP) is a chronic inflammatory autoimmune skin disorder that commonly affects the skin, oral mucosa, genital mucosa, scalp, and nails. Vitamin D has properties of anti-inflammatory with immunomodulatory effects and some antioxidant effects. Objectives: This research aimed to assess the level of serum vitamin D among patients with Lichen Plans and also to do a comparison with the healthy control group < /p> Subjects and Methods: A case-control study was carried out. Thirty-three patients with Lichen planus and 30 normal healthy controls were involved in this study. The blood samples were taken and collected to assess the serum levels of 25-hydroxy vitamin D, from all the patients and the control subjects. Results: The Mean serum level of Vitamin D in patients with LP was 16.7 ± 6.0, which was significantly lower than that of normal subjects (21.4 ± 8.9), with P value = 0.029. Conclusion: Our research showed a lower level of Vit D among patients with LP. Also, there may be other factors that play roles in provoking LP and its immunopathogenesis.