Background: Twenty percent to forty percent of those who have laparoscopic cholecystectomy experience perforation of the gallbladder. The incidence of gallbladder perforation and its intraoperative implications may be reduced by using ultrasound to dissect the gallbladder bed during laparoscopic cholecystectomy, which might enhance surgical quality. Objectives: This study aimed to compare between the conventional electrocautery dissection technique and the ultrasonic gall bladder dissection. Methods: The research included 120 adult patients with symptomatic gallstone disease who were candidates for laparoscopic cholecystectomy. Each patient's demographic information, as well as clinical, radiological, and laboratory data, were evaluated. Study was conducted in Safa Almadinah Hospital in Saudi Arabia between June 2019 and May 2022. Results: There was no major difference between the two groups in terms of baseline characteristics and demographic data. Before surgery, ultrasonography data showed no major differences between the two groups. There was significant increase in the incidence of complications in Electrocautery group except for the need to insert hemostatics and stone leakage there was no significant difference between the two groups. Conclusion: In order to improve the surgical course of laparoscopic cholecystectomy, ultrasonic dissection is used. This is because ultrasonic dissection is both safe and effective in minimizing the risk of gallbladder perforation, as well as the time needed and the possibility for complications.