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260751

Comparative Study for Use of Steroids in Treatment of Sudden Sensorineural Hearing Loss in COVID19 Patients

Article

Last updated: 03 Jan 2025

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Abstract

Introduction: Viruses are identified to lead to neurological manifestation, like anosmia, facial paralysis and sudden sensorineural hearing loss (SSNHL). Throughout the preceding SARS epidemic, corona-viruses were stated be accompanied with losses of smell and taste senses because of neural injuries. Aim: This research aims to study the existence of (SARS-CoV-2) in cases with only SSHNL throughout the COVID19 pandemic and effectiveness on intratympanic steroid injections on development of cases. Methods: This work involved 20-cases with the single complaint of unilateral SSNHL to the otolaryngology out-patient clinics. The cases were directed to be assessed for SARS-CoV-2 by real time polymerase chain reactions (RT-PCR) test. Cases received systemic steroids, intratympanic steroids or combined and were then audiologically assessed. Results: RT-PCR test for SARS-CoV-2 was positive in 13 cases. A positive responding to COVID19-definite therapy in the SARS-CoV-2 positive SSNHL cases has been observed. Most of cases received intratympanic steroids showed significant improvement than non-received (p=0.005). Also, cases received combined intratympanic and systemic steroids showed significant improvement than non-received (p=0.021), while improvement in cases received systemic steroids or vasodilators showed no statistical significant difference than non-received (p=0.306 and 0.595, respectively). Conclusion: It must be recalled that nonspecific signs like SSNHL can be the only symptom with which to know a COVID19 case. Recognition of such nonspecific presentations of COVID19 cases is crucial throughout this pandemic time for avoiding infectious spreading via isolations and early initiations of COVID19 targeted therapy.  

DOI

10.21608/ejhm.2022.260751

Keywords

COVID19, Sudden sensorineural hearing loss, pandemic, SARS-CoV-2, intratympanic steroids

Authors

First Name

Michael

Last Name

Rezk

MiddleName

-

Affiliation

-

Email

michaelrezkent@gmail.com

City

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Orcid

-

First Name

Mina

Last Name

Saleeb

MiddleName

Fayez

Affiliation

Ain Shams university

Email

minafayezw@gmail.com

City

-

Orcid

-

Volume

89

Article Issue

1

Related Issue

36332

Issue Date

2022-10-01

Receive Date

2022-09-22

Publish Date

2022-10-01

Page Start

4,848

Page End

4,853

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_260751.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=260751

Order

112

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparative Study for Use of Steroids in Treatment of Sudden Sensorineural Hearing Loss in COVID19 Patients

Details

Type

Article

Created At

22 Jan 2023