Background: Cervical cancer is 2^nd prevalent cancer between females in developed countries. Colposcopy is a simple diagnostic process used to look at cervix, vagina and vulva with illumination and magnification of the view, Aim and objectives: This study aimed to investigate the role of colposcopy performance according to the standard guidelines in enhancing patient care and outcomes according to National Health Service Cervical screening program. Subjects & methods: This cross-sectional observational research was carried out on 100 studied cases who came to the Outpatient Colposcopy Unit of Al-Azhar University Hospital (Assiut). Result: As regards excisional form of biopsy, recording ectocervix when substituted with high-grade abnormality and when low grade coloposcopic variation was related to high grade dyskaryosis or worse, there were significant different from guidelines (p=0.214 & 0.003 respectively), Conclusion: In selected studied cases, colposcopy is critical to "see-and-treat" method of treating great-grade cervical cytologic abnormalities,